Pregnancy in space: studying stem cells in zero gravity may determine whether it’s safe

This article was originally published at The Conversation. (opens in new tab) The contributed the article to Space.com’s Expert Voices: Op-Ed & Insights. Joanna Bridger (opens in new tab)Director of the Center for Genome Engineering and Maintenance (CenGEM), Professor of Genome Organisation, Brunel University LondonEmmanouil Karteris (opens in new tab)Reader in Biomedical Sciences, Brunel University … Read more

Widening participation in STEM requires an attitude change

Credit: Unsplash/CC0 Public Domain Students rule themselves out of, or in to, STEM (Science, Technology, Engineering and Mathematics) disciplines, based on stereotyped views of what makes a typical student, a new study has found. New research from the University of Reading has found a social hierarchy in STEM, as well as narrow but differing views … Read more

New approach more than doubles stem cell editing efficiency, researchers report

A Penn State student measures modified RNA concentration with a spectrophotometer. The researchers found that modified RNA improves the efficiency of CRISPR-Cas9 delivery. Credit: Kate Myers/Penn State A Penn State-led team of interdisciplinary researchers has developed techniques to improve the efficiency of CRISPR-Cas9, the genome editing technique that earned the Nobel Prize in 2020. While … Read more

See-through zebrafish, new imaging method put blood stem cells in high-resolution spotlight

Tracing features in a large 3D electron microscopy dataset reveals a zebrafish blood stem cell (in green) and its surrounding niche support cells, a group photo method that will help researchers understand factors that contribute to blood stem cell health—which could in turn help develop therapies for blood diseases and cancers. Credit: Keunyoung Kim For … Read more

Do stem cells grow better in space?

This photo released by Roscosmos Space Agency Press Service shows the International Space Station on March 30, 2022, photographed by the crew of a Russian Soyuz MS-19 spaceship after undocking from the station. Scientists at Cedars-Sinai Medical Center in Los Angeles are trying to find new ways to produce huge batches of a type of … Read more

Board game developed by scientists is winning plaudits for inspiring students to consider STEM careers

Diamond: The Game. Credit: Diamond Light Source Ltd A team of scientists and a games specialist have designed “Diamond: The Game,” a board game developed to give secondary school students a chance to explore a broad range of STEM scientific careers and subjects. This is achieved through firsthand experience of the different aspects of working … Read more

Ketogenic diet helps mouse muscle stem cells survive stress, study finds

Cell Metabolism (2022). DOI: 10.1016/j.cmet.2022.04.012″ width=”800″ height=”530″/> Graphical abstract. Credit: Cell Metabolism (2022). DOI: 10.1016/j.cmet.2022.04.012 Fasting sends muscle stem cells into a deep resting state that slows muscle repair but also makes them more resistant to stress, according to a Stanford Medicine study of laboratory mice. The protective effect can also be achieved by feeding … Read more

Study identifies how blood stem cells maintain their fate

Image shows mouse blood cells — a mix of stem and progenitor cells, differentiated neutrophils and mixed identity cells. Credit: Meijuan Chen, Cheloufi lab, UC Riverside. Understanding the molecular mechanisms that specify and maintain the identities of more than 200 cell types of the human body is arguably one of the most fundamental problems in … Read more