Artificial intelligence tools predict DNA’s regulatory role and 3D structure

Nature Genetics (2022). DOI: 10.1038/s41588-022-01102-2″ width=”800″ height=”530″/> Disease regulatory mutations are predicted to promoter, CTCF and tissue-specific enhancer sequence classes. Sequence class-level mutation effects of pathogenic noncoding HGMD mutations were plotted. A polar coordinate system was used, where the radial coordinate indicates the sequence class-level effects. Each dot represents a mutation and mutations inside the … Read more

‘Not all is lost’ in climate change fight after Supreme Court limits EPA’s regulatory power

Credit: Pixabay/CC0 Public Domain The Supreme Court Thursday issued a ruling limiting the Environmental Protection Agency’s ability to regulate carbon emissions from power plants. The 6-3 vote along party lines called into question the federal agency’s regulatory authority by suggesting that it does not have the power to cap carbon emissions from power plants through … Read more