Tailoring the particle sizes of Pt₅Ce alloy nanoparticles for the oxygen reduction reaction

by Beijing Zhongke Journal Publication Co. Ltd. 4+ ions are reduced to Pt nanoparticles; Period 2, when Pt nanoparticles react with the Ce2(CN2)3 to form Pt5Ce; and Period 3, when the Pt5Ce particles grow further due to the prolonged heat-treatment at 650 °C. Art by Hu’s group. Credit: Beijing Zhongke Journal Publication Co. Ltd.” width=”800″ … Read more

How different cancer cells respond to drug-delivering nanoparticles

Science (2022). DOI: 10.1126/science.abm5551″ width=”800″ height=”530″/> Using a curated nanoparticle library, the researchers screened nanoparticle-cell interaction profiles of hundreds of cancer cells simultaneously. By incorporating omics annotation, they identified biological features, or biomarkers, that mediate nanoparticle delivery to cells. They generated trafficking networks and discovered a biologic regulator of lipid-based nanoparticle delivery. PLGA, polylactide-co-glycolide; PS, … Read more

Influence of nanoparticles, surrounding ions on formation of β-sheet structure in amyloid β proteins

Infrared (FT-IR) spectra and β-sheet ratio of Aβ peptides interacting with CeF3 NPs. The effect of CeF3 nanoparticles on amyloid beta protein structure is measured directly with FT-IR spectroscopy. The formation of secondary structure shows up as a feature in the IR spectrum. Credit: Masakazu Umezawa / Tokyo University of Science, License type: CC BY … Read more

New machine learning model predicts how nanoparticles interact with proteins

The model predicted how a zinc oxide nanopyramid interrupts a protein that contributes to metabolism in MRSA (methicillin resistant Staphylococcus aureus), a common strain that causes antibiotic resistant infections. Credit: Minjeong Cha and Emine Sumeyra Turali Emre, Kotov Lab With antibiotic-resistant infections on the rise and a continually morphing pandemic virus, it’s easy to see … Read more