New method allows scientists to determine all the molecules present in the lysosomes of mice

A cartoon representation of the new method, which allows scientists to isolate the lysosomes (left) of any cell in a mouse to analyze and identify using mass spectrometry (right) all the molecules inside them. Credit: Cindy Lin Small but mighty, lysosomes play a surprisingly important role in cells despite their diminutive size. Making up only … Read more

Anti-aging clues lurk in lysosomes, the recycling centers of the cell

0.05), ***P < 0.001 by log-rank test, 60–120 worms per replicate. See Supplementary Tables 4 and 5 for full lifespan data. In c, error bars represent mean ± standard error of the mean (sem), n = 3 biologically independent samples, ****P < 0.0001 by two-tailed Student's t-test, ~2,000 worms per replicate. In e, error bars ... Read more