Oldest vertebrate fossil heart ever found tells a 380 million-year-old story of evolution

The Gogo fish fossils used in this study were discovered within rocks found in the Kimberley. Credit: Curtin Universty In the limestone ranges of Western Australia’s Kimberley region, near the town of Fitzroy Crossing, you’ll find one of the world’s best-preserved ancient reef complexes. Here lie the remnants of myriad prehistoric marine animals, including placoderms, … Read more

380-million-year-old heart illuminates evolutionary history

The Gogo fish fossil where the 380-million-year-old, 3D preserved heart was discovered by researchers. Pictured at the WA Museum. Credit: Yasmine Phillips, Curtin University Researchers have discovered a 380-million-year-old heart—the oldest ever found—alongside a separate fossilized stomach, intestine and liver in an ancient jawed fish, shedding new light on the evolution of our own bodies. … Read more

Researchers find spaceflight may be associated with DNA mutations, increased risk of heart disease and cancer

a) We identified somatic mutations in known clonal hematopoiesis of indeterminate potential (CHIP) driver genes using peripheral blood mononuclear cells isolated from 14 astronauts who flew short space Shuttle missions lasting a median of 12 days between 1998–2001. Created with BioRender.com. b) Number of somatic nonsynonymous single nucleotide variants (SNVs) in CHIP-driver genes harbored per … Read more

‘Star factory’ at Milky Way’s heart seen for the first time

Astronomers have reconstructed the history of star formation at the center of the Milky Way for the first time, finding that starbirth radiated outwards from the galaxy’s heart. The results also revealed that most young stars in the densely packed galactic center formed with only loose associations and drifted further apart over the course of … Read more

The Tin Man gets a heart in ‘The Orville’ Season 3 episode 7

Warning: Spoilers ahead for “The Orville” season 3, episode 7 With “Star Trek: Strange New Worlds” wrapping up, “The Orville” is the best new live-action sci-fi currently on TV — and even this season of “The Orville” only has three more episodes left. No, we haven’t forgotten about “For All Mankind,” we just don’t think … Read more

Team invents new anticoagulant platform, offering hope for advances for heart surgery, dialysis, other procedures

RNA-DNA nanofibers have been designed to bind and inactivate thrombin and due to their size have a prolonged circulation in bloodstream. This induced anticoagulation process can be reversed by the kill switch mechanism that also results in production of smaller complexes for accelerated renal excretion. Credit: UNC Charlotte While blood clotting is important to prevent … Read more

First cryo-EM structures of angiotensin-converting enzyme pave the way for better drugs to treat heart disease

Cryo-EM structures of the hourglass-shaped ACE monomer (one protein copy; left) and dimer (two interacting protein copies; middle). A flexible loop (yellow; protein center) acts as a hub for communication between different areas of the protein. Dimerization is like a ‘kiss of death’ since it triggers conformational changes in the protein core that likely inactivate … Read more

A cloudless future? The mystery at the heart of climate forecasts

Shallow clouds formed by fine-scale eddies as observed in nature. Researchers are using advanced computing to add higher-resolution cloud dynamics into global simulations. Credit: Creative commons We hear a lot about how climate change will change the land, sea, and ice. But how will it affect clouds? “Low clouds could dry up and shrink like … Read more

This is it! Meet the Supermassive Black Hole at the Heart of the Milky Way

On April 10th, 2019, the international consortium known as the Event Horizon Telescope (EHT) announced the first-ever image of a supermassive black hole (SMBH). The image showed the bright disk surrounding the black hole at the center of the M87 galaxy (aka. Virgo A). In 2021, they followed up on this by acquiring an image … Read more