Mutation in key molecules could stop gonorrhea infection

mBio (2022). DOI: 10.1128/mbio.01670-22″ width=”800″ height=”389″/> Variant tdfJ genes are expressed from an inducible ectopic site in the gonococcal chromosome. Wild-type and mutated forms of tdfJ were cloned into a complementation vector designed to insert into an ectopic site of the gonococcal chromosome between the aspC and lctP loci. This construct contains an IPTG-inducible promoter … Read more

Did gonorrhea give us grandparents?

Neisseria gonorrhoeae bacteria may have driven the evolution of human gene variants that protect against dementia. Credit: National Institute of Allergy and Infectious Diseases, National Institutes of Health Researchers at University of California San Diego School of Medicine previously found a set of human gene mutations that protect older adults against cognitive decline and dementia. … Read more