Scientists engineer mosquitoes that can’t spread malaria

Professor George Christophides holds a cage of mosquitoes. Credit: Imperial College London Scientists have engineered mosquitoes that slow the growth of malaria-causing parasites in their gut, preventing transmission of the disease to humans. The genetic modification mosquitoes to produce compounds in their guts that stunt the growth of parasites, meaning they are unlikely to reach … Read more

Researchers engineer first sustainable chromosome changes in mice

By fusing two medium-sized chromosomes, researchers produced the first sustainable engineered karyotype for lab mice. This mouse carries two chromosomes fused together. Credit: WANG Qiang Evolutionary chromosomal changes may take a million years in nature, but researchers are now reporting a novel technique enabling programmable chromosome fusion that has successfully produced mice with genetic changes … Read more

In control of chaos to engineer high-entropy ceramics

Assembly line: A different chemical mixture is created in each of the droplets within the “Tubular flow reactor”—under exactly the same boundary conditions. Credit: Empa Nature strives for chaos. That’s a nice, comforting phrase when yet another coffee cup has toppled over the computer keyboard and you imagine you could wish the sugary, milky brew … Read more

Engineer uses ancient art of origami to solve a very modern aerospace problem

A starshade can help find exoplanets, but getting one inside a rocket is a challenge. Credit: Manan Arya If you’ve ever made an origami paper crane, using folds and creases to transform a square piece of craft paper into the delicate long-necked bird, it may seem odd that those same folding techniques are being used … Read more

Scientists engineer synthetic DNA to study ‘architect’ genes

Science (2022)” width=”800″ height=”450″/> Using synthetic DNA, the researchers created an artificial Hox cluster. The cluster is divided into two: active (to the left of the vertical line) and inactive (to the right), illustrating how Hox genes help cells know where they should be in the body. Credit: Pinglay et al., Science (2022) Researchers at … Read more

Scientists engineer quantum processor to emulate a small organic molecule

Lead researcher and former Australian of the Year, Scientia Professor Michelle Simmons. Credit: SQC A team of quantum computer physicists at UNSW Sydney has engineered a quantum processor at the atomic scale to simulate the behavior of a small organic molecule, solving a challenge set some 60 years ago by theoretical physicist Richard Feynman. The … Read more

Scientists engineer new tools to electronically control gene expression

Illustration of how the system works. Credit: Imperial College London Researchers, led by experts at Imperial College London, have developed a new method that allows gene expression to be precisely altered by supplying and removing electrons. This could help control biomedical implants in the body or reactions in large ‘bioreactors’ that produce drugs and other … Read more