How different cancer cells respond to drug-delivering nanoparticles

Science (2022). DOI: 10.1126/science.abm5551″ width=”800″ height=”530″/> Using a curated nanoparticle library, the researchers screened nanoparticle-cell interaction profiles of hundreds of cancer cells simultaneously. By incorporating omics annotation, they identified biological features, or biomarkers, that mediate nanoparticle delivery to cells. They generated trafficking networks and discovered a biologic regulator of lipid-based nanoparticle delivery. PLGA, polylactide-co-glycolide; PS, … Read more