Concise synthesis of developed pleurotin

A photoredox radical epimerization generates the tetracyclic skeleton of pleurotin. Credit: The Sorensen Lab From the perspective of chemists, pleurotin is an intriguing molecule. There is strong evidence of untapped therapeutic properties as a tumor inhibitor and antibiotic. It has a fascinating complex structure (six rings! eight stereocenters!). And it has been difficult to synthesize … Read more